请问下大家下面那个with which的用法Over the last 40 years there has been a great increase not only in the number of agricultural pesticides in use but also in the care and sophistication with which they are used by farmers.一直看不懂

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请问下大家下面那个with which的用法Over the last 40 years there has been a great increase not only in the number of agricultural pesticides in use but also in the care and sophistication with which they are used by farmers.一直看不懂
请问下大家下面那个with which的用法
Over the last 40 years there has been a great increase not only in the number of agricultural pesticides in use but also in the care and sophistication with which they are used by farmers.
一直看不懂介词+which结构,那位得道高人来帮我指点下~

请问下大家下面那个with which的用法Over the last 40 years there has been a great increase not only in the number of agricultural pesticides in use but also in the care and sophistication with which they are used by farmers.一直看不懂
with which 引导的是定语从句 并且在定从中 作状语
也就是 with the care and sophistication they are used by farmers

which应该指的是前面的care and sophistication

先来看着句子里的几个内容：
a great increase in the number of agricultural pesticides in use
a great increase in the care and sophistication
agricultural pesticides are used by farmers with care and sop...

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先来看着句子里的几个内容：
a great increase in the number of agricultural pesticides in use
a great increase in the care and sophistication
agricultural pesticides are used by farmers with care and sophistication

这样就清楚了：which they are used by farmers 作定语修饰 care and sophistication，而 with 被放在了这个从句的前面（很传统的语法）。同样的结构也有把它放在句末的。但在这个句子里放在句末就很别扭。

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